There has been an increase in open access activities in chemistry in recent years (30 April 2025). For example, large specialist publishers have converted several journals to open access, and chemical societies have intensified their activities towards open access.
PLOS ONE (Chemistry Section): While broad in scope, PLOS ONE is a fully open-access journal that publishes a large volume of peer-reviewed research across all scientific and medical disciplines, including a dedicated section for chemistry.
RSC Advances (Royal Society of Chemistry): Published by the Royal Society of Chemistry, this is a broad scope, fully open-access journal covering multidisciplinary topics in the chemical sciences. It's a very active journal.
Scientific Reports (Chemistry Section): Another open-access journal from the Nature Portfolio, covering a wide range of scientific disciplines, with a substantial portion dedicated to chemistry research.